CD BioSciences Develops Customized Toehold Switch Synthesis Service to Advance Scientific and Medical Research

December 09 21:31 2022
CD BioSciences announced the release of a customized toehold switch synthesis service to support scientific and medical research.

New York, USA – December 9, 2022 – Toehold Switches Platform, the division of CD BioSciences, is dedicated to providing toehold switches design, optimization, and construction services to domestic and international clients, providing solid technical support to advance their relevant research. With cutting-edge technology and a professional scientific team, CD BioSciences also provides development services for a variety of sensors based on toehold switches. Recently, CD BioSciences announced the release of a customized toehold switch synthesis service to support scientific and medical research.

Chemical synthesis of toehold switches is more difficult due to the low efficiency of RNA base coupling, easy product disassembly, and the need to ligate reporter genes. However, CD BioSciences, with its first-class research team, advanced machines, and a professional foot switch synthesis system, evaluates the toehold switch sequence for a specific trigger RNA sequence and provides a clean experiment to synthesize the sequence that meets the requirements, and the toehold that does not meet the requirements will be optimized before synthesis.

Depending on the research purpose, CD BioSciences is able to modify the footswitch RNA in different ways:

• If a diagnostic test needs to be developed, CD BioSciences can attach fluorescent reporter molecules to the footswitch.

• If a biosynthetic tool needs to be developed, CD BioSciences can link to the synthetic protein gene on the foot switch.

• If gene therapy needs to be developed, CD BioSciences can link specific gene segments for customers on the foot switch.

CD BioSciences provides a one-stop service from foot switch design to integration. Customers can choose to provide information such as trigger RNA sequence, research target, host cell type, etc. CD BioSciences will provide toehold switch design, optimization, and synthesis services. Alternatively, the customer provides the sequence of the footswitch to be synthesized, along with yield and purity requirements, and CD BioSciences will provide the synthesis of the toehold switches.

CD BioSciences follows strict quality requirements to ensure no RNase contamination during toehold switch RNA synthesis and offers a wide range of services to meet any requirement for toehold switch RNA, including reporter gene modification, fluorescent labeling, and ligation.

“Our toehold switches can be widely used as detection sensors to detect small molecules, proteins, nucleic acids as well as programmable RNA tools in fields such as targeted therapy development.” said Marcia Brady, the marketing director of CD BioSciences, she also added, “we are capable to develop customized solutions for specific requirements.”

About CD BioSciences

As one of the key businesses of CD BioSciences, Toehold Switch has established an advanced technology platform, a scientific service system and a strong research team. Foot switches can be used in various fields such as virus detection, bacterial detection, biomarker detection and genetic research. CD BioSciences can provide you with comprehensive services in these application areas.

Media Contact
Company Name: CD BioSciences
Contact Person: Marcia Brady
Email: Send Email
Phone: 1-631-372-1052
Country: United States
Website: https://www.toehold-switch.com