The Pancreatic Endocrine Tumor market report provides current treatment practices, emerging drugs, Pancreatic Endocrine Tumor market share of the individual therapies, current and forecasted Pancreatic Endocrine Tumor market Size from 2017 to 2030 segmented by seven major markets. The Report also covers current Pancreatic Endocrine Tumor treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assesses the underlying potential of the market.
Pancreatic Endocrine Tumor Overview
Pancreatic Endocrine tumors are well-differentiated, low, intermediate, or high-grade neuroendocrine neoplasm, which is composed of cells showing minimal to moderate atypia, displaying organoid patterns, lacking necrosis, and expressing general markers of neuroendocrine differentiation (diffuse and intense synaptophysin and usually also chromogranin A staining) and hormones (usually intense but not necessarily diffuse), either orthotopic or ectopic to the pancreas.
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Pancreatic Endocrine Tumor Market: Disease
WHO grading system has divided PNET, based on Mitotic count, Ki-67 index in to well-differentiated tumors (which includes G1, G2), and poorly differentiated tumors (G3); have 2-20 or more mitoses and a Ki-67 index of 3 to 20% or higher, with 5year survival rate 85% or 9% respectively.
Pancreatic Endocrine Tumor Market: Size
The increase in Market Size is a direct consequence of increasing prevalent population of PNETs patients in the 7MM, along with expected entry of improved diagnostic methods such as Octreoscan and the recently launched Netspot will have impact on market size.
Pancreatic Endocrine Tumor Market: Symptoms
In the symptom based prevalence of PNETs, Gastrinoma has reported to be occur in highest cases, followed by Insulinoma, Glucagonoma, VIPoma and Somatostatinoma. The total prevalent cases of Non-functional PNET exceeds the Functional PNET with 9:1 ratio respectively.
Pancreatic Endocrine Tumor Market: Insights
Pancreatic lesions can be detected on transabdominal ultrasound; however, contrast-enhanced CT is the most helpful study in the evaluation or detection of PNET. PNETs are characterized with contrast uptake during an early arterial phase with ‘washout’ during the portal venous phase, a similar appearance is seen in liver metastases if present.
Pancreatic Endocrine Tumor Market: Treatment
The treatment landscape of PNET comprises of surgical as well as pharmacotherapies. Although surgical therapies occupy the major share to date and are mainly from the first line of defense, but a large section of the patient population present with advanced disease and are not candidates for resection. In such cases, therapeutic modalities come into play which are primarily symptomatic in nature.
Pancreatic Endocrine Tumor Market: Forecast
Despite all these available treatment options, the clinical pipeline for PNET seems weak at present, researchers, as well as key players such as Hutchinson Medipharma, TaiRx, Inc, and others, are actively focused on the development of novel therapies for the treatment of PNET.
Pancreatic Endocrine Tumor Market: Report Scope
Table of content
1. Key Insights
2. Executive Summary of Pancreatic Endocrine Tumor
3. Competitive Intelligence Analysis for Pancreatic Endocrine Tumor
4. Pancreatic Endocrine Tumor: Market Overview at a Glance
5. Pancreatic Endocrine Tumor: Disease Background and Overview
6. Patient Journey
7. Pancreatic Endocrine Tumor Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Unmet Needs
10. Key Endpoints of Pancreatic Endocrine Tumor Treatment
11. Marketed Products
12. Emerging Therapies
13. Pancreatic Endocrine Tumor: Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview of Pancreatic Endocrine Tumor
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight
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